Наукові праці. Кафедра дерматології, венерології і медичної косметології
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Browsing Наукові праці. Кафедра дерматології, венерології і медичної косметології by Title
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Item Alternative treatment for alopecia(Journal of Education, Health and Sport., 2017) Tatuzian, Yevheniia; Bilovol, Alla; Tkachenko, SvitlanaBeautiful, well-groomed appearance often ensures greater success and great opportunity. Therefore, a successful woman understands how important it is to pay attention not only to his intellectual development, but also to keep their external beauty and attractiveness, youthfulness and health. In recent years there is a very effective method to combat all signs of skin aging, which gives the result almost immediately after the first application and does not require rehabilitation period. This procedure is called plasmotherapy, which you can use to solve many problems not only aesthetics but skin health.Item Application of dermatoscopy in the management of scabies(2016) Bilovol, Alla; Tkachenko, Svitlana; Volovik, OlgaItem Assessment of the epidermal growth factor level in blood of patients with psoriatic arthritis during the treatment course(2018-09) Havryliuk, OleksandraItem Clinical and pathogenetic parallels between psoriasis and lichen planus(NPhaU, 2020) Bilovol, Alla; Tkachenko, Svitlana; Berehova, AllaItem Clinical feature of psoriasis with comorbid arterial hypertension(2017) Bilovol, Alla; Tkachenko, SvitlanaItem Comparative Characteristics of Metabolic Parameters in Patients with Psoriasis and Lichen Planus(2022-02) Bilovol, Alla; Tkachenko, Svitlana; Havryliuk, Oleksandra; Berehova, Alla; Pustova, Nataliia; Kolhanova, Nataliia; Drozd, YuliaItem Content of mediatirs of trophotropic systems at psoriastic patients with different degree of severity of clinical event(2016) Berehova, AllaPsoriasis as one of the most widely-spread dermatosis is still an urgent problem of modern dermatology. Aim. To assess, on the different levels of psoriasis’ clinical event, condition of trophotropic system by the detection serotonin’s, histamine’s and histidine’s content in the daily urine. Materials and methods. 97 patients were examined, by the PASI classification: I-35 patients with light degree of severity, II – 32 with mean, III – 30 with severe. Control group – 30 relatively healthy people. Serotonin’s, histamine’s and histidine’s detection were made in one test of daily urine according to the guideline of C.I. Gerasimova. On the first stage their partition were made with the method of column chromatography. Contest was calculated by the fluorescence standard. Results. Received results indicate about considerable participation of histamine reactive system on the psoriasis’ pathogenesis. Implementation of last is connected with strong psycho-emotional stress, which develops at psoriasis patients in the response, first of all, for itching. Discovered trophotropic mediators’ response: histamine and serotonin in the process of psoriasis’ development has adaptive character. Indirect predominance of histamine reactive system above serotonergic system was marked. In psoriasis’ pathogenesis a leading part play disturbances of vegetative mediators’ balance, in the conditions of its progress lead to the deadaptation and development of pathological reaction, which hook up regulative and metabolic processes. Conclusions. Progressing of psoriasis if followed by gradual activation at transition from light to severe degree of clinical event of trophotropic functions. Given results put up a question about modern correction of condition and trophotropic systems at psoriatic patients with the aim of slowing down its progression.Item Evaluation of metal ions content in blood serum, erythrocytes and urine of patients with psoriasis associated with arterial hypertension(2019) Havryliuk, Oleksandra; Bilovol, Alla; Tkachenko, SvitlanaItem Factitious disorders in children: clinical and therapeutic considerations(2019) Jafferany, Mohammad; Kobusiewicz, Aleksandra; Ferreira, Barbara; Garan, Serpil; Havryliuk, OleksandraThere is considerable lack of awareness about child and adolescent population intentionally producing dermatological symptoms and this unique group has remained underreported. The aim: this review focuses on educating dermatologists about the pathogenesis, symptomatology and management options of factitious disorders. Materials and methods: Medline search was conducted for last two decades and articles containing words factitious disorders and dermatitis artefacta were identified. Results: Children with factitious disorders suffer from other psychiatric disorders, particularly depression and borderline personality traits. The prevalence ranges from 0.5-2%. Majority of children and adolescents who engage in self-injurious behaviors do not intend to commit suicide, instead they use their self-injurious behavior as an appeal for help or a non-verbal form of communication. Conclusions: Patients should not be confronted to explore the underlying psychological conflicts, rather gentle, non-judgmental and empathic approach be utilized for a good therapeutic rapport. High index of suspicion on provider’s part is a key to diagnosis. Along with dermatological care, psychopharmacological interventions and psychotherapeutic techniques have proven helpful in this population.Item Features of the Neurological Status of Patients with Latent Late Syphilis(2021-06-02) Havryliuk, Oleksandra; Nikitenko, Inna; Bondarenko, Glib; Scherbakova, Yuliia; Kutova, Valentyna; Bezruchenko, OlexiyItem Hormonal disbalance as the reason of an androgenic alopetion(2013-09-30) Khristenko, Nadia; Bilovol, Alla; Berehova, Alla; Kolhanova, NataliiaItem Lichen planus and comorbid conditions (a review of literature)(2019) Bilovol, Alla; Tkachenko, Svitlana; Havryliuk, Oleksandra; Berehova, Alla; Tatuzian, Yevheniia; Kolhanova, Nataliia; Stetsenko, SvitlanaIntroduction. The studying of the comorbidity of skin diseases is a priority scientific direction in modern dermatology. Comorbid conditions aggravate the course of the underlying disease, reduce the effectiveness of diagnosis and treatment can lead to chronization of the process, disability of patients. Understanding of the commonality of pathogenesis and the mutually complicating nature of comorbidity makes a possible to prescribe individual rational treatment. The aim of the study was search and analysis of the data of review, experimental and clinical scientific and medical publications on the issues of the comorbidity of LP. Materials and methods: an analysis of the studying of the scientific and medical literature was shown. Searching was carried out through the PubMed/MEDLINE portal from the databases of the National Center Biotechnology Information, U. S. National Library of Medicine, National Institute for Health and Clinical Excellence, as well as the portals «Scientific Electronic Library eLIBRARY.RU», «Russian Science Citation Index (RSCI)» and «Index Copernicus». Conclusions. The main global trends of comorbidity of LP are determined. The results of these studies can form the basis for updating of clinical guidelines for the management of patients with LP at the international and local levels.Item Modern approaches to the treatment of psoriasis associated with cardio metabolic disorders(2015-03) Bilovol, Alla; Tkachenko, SvitlanaРиск кардиометаболических нарушений у больных псориазом очень высок, что ассоциируется также и с высокой смертностью. Целью данного исследования было изучение коморбидности псориаза и кардиометаболических нарушений для разработки патогенетического лечения и оценки влияния метаболической терапии на дерматологические и кардиометаболические показатели у больных псориазом, ассоциированным с кардиометаболическими нарушениями. Исследование проводили в двух группах больных псориазом. Различные кардиометаболические нарушения были выявлены у 144 пациентов 1 группы и 68 пациентов 2 группы, что составило 78,6 % и 88,5 % соответственно. Пациенты 1 группы (183 исследуемых) получали традиционное лечение псориаза, пациенты 2 группы (78 исследуемых) получали метаболическую терапию. Статистически значимой разницы динамки индексов в процессе лечения псориаза первой и второй групп выявлено не было (р>0,1). – 41 % и 44 % соответственно. Более выраженное улучшение по всем кардиометаболическим показателям было выявлено в группе пациентов, получавших метаболическую терапию, особенно улучшение сна (22,9 %), снижение артериального давления (59,7 %), уменьшение головных болей (43,0 %) и одышки (22,9 %). Позитивная динамика по ключевым параметрам крови, отражающим липидный и углеводный обмен, не отличалась статистически между группами. Использование метаболической терапии псориаза, ассоциированного с кардиометаболическими нарушениями, дает возможность избежать назначения медикаментозной коррекции сопутствующей патологии или сократить уже назначенную симптоматическую терапию.Item Modern clinical and anamnestical aspects of lichenoid dermatoses(Дерматологія та венерологія, 2021) Bilovol, Alla; Tkachenko, Svitlana; Berehova, AllaItem Optimization of therapy of comorbidity of psoriasis and cardio vascular disorders(2017) Bilovol, Alla; Tkachenko, Svitlana; Tatuzian, YevheniiaItem Perspective treatment of psoriasis with arterial hypertension comorbidity(2019) Bilovol, Alla; Tkachenko, SvitlanaItem Possible role of vitamin D in pathogenesis of lichenoid dermatoses (a review of literature)(2020-02) Bilovol, Alla; Tkachenko, Svitlana; Havryliuk, Oleksandra; Berehova, Alla; Kolhanova, Nataliia; Kashtan, KaterynaIntroduction. The studying of the possible role of vitamin D (VD) in pathogenesis of lichenoid dermatoses is a priority scientific direction in modern dermatology. The possible pathogenic participation of VD in the development of these dermatoses can discover the new prospects of systemic treatment. The aim of the study was search and analysis of the data of review, experimental and clinical scientific and medical publications on the issues of the possible role of VD in pathogenesis of lichenoid dermatoses. Materials and methods: an analysis of the studying of the scientific and medical literature was shown. Searching was carried out through the PubMed/MEDLINE portal from the databases of the National Center Biotechnology Information, Web of Science Core Collection, U. S. National Library of Medicine, National Institute for Health and Clinical Excellence, as well as the portals «Scientific Electronic Library eLIBRARY.RU», «Russian Science Citation Index (RSCI)» and «Index Copernicus». Conclusions. the results of studies had convincingly demonstrated that deficiency of VD in the blood, decrease vitamin D receptors activity can lead to development of lichenoid dermatoses.Item Psychodermatology in Ukraine and Belarus: an Eastern European perspective(2019) Havryliuk, Oleksandra; Jafferany, Mohammad; Adaskevich, Uladzimir; Aksana, MarozavaPatients with skin diseases often have psychiatric problems that require appropriate assessment and correction, but these symptoms are frequently overlooked and undertreated. The aim of this study was to assess the level of training, awareness and attitude about psychocutaneous disorders among dermatologists in Eastern Europe. The survey study included 396 dermatologists. Only 16.16 % of the respondents reported a clear understanding of term psychodermatology, 47.47% of them no training and had attended no educational events on psychodermatology. 17. 8 % of dermatologists never referred such patients to psychiatrists. Around 85 % of the respondents were unaware of any psychodermatology resources. Overall 61 % of the dermatologists expressed interest in attending any kind of CME activity on psychodermatology. Survey results showed that knowledge about the diagnosis and treatment for psychocutaneous disorders is lacking. These findings support the need for improvement in training in psychodermatology and the holding of regular CME events.Item Psychodermatology: awareness, understanding and attitude of dermatologists in Eastern Europe(2018-09) Havryliuk, Oleksandra