ISSN 2310-8363

Репозитарій Харківського національного медичного університету – це відкритий електронний архів академічних текстів, матеріалів наукового та навчально-методичного призначення, створених науковцями, викладачами, іншими працівниками університету та здобувачами

З усіх питань щодо Репозитарію ХНМУ звертайтеся до координатора Тетяни Павленко за адресою: repository@knmu.edu.ua

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    Diagnostic challenges of coexisting AIHA and Hodgkin lymphoma in an 11-year-old boy
    (2026) Makieieva,N.; Koval,V.; Boldyrieva,O.; Kucherenko,M.; Derkach, A.
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    Surgeons’ practices and preferences for performing right hemicolectomy for colorectal cancer: results from the SuPrHem survey
    (2026) Tokoto, Pierre-Alain; Meyer, Elin; Gialamas, Eleftherios; Meurette, Guillaume; Liot, Emilie; Davies, Justin; Ris, Frеdеric; Kryvoruchko, Ihor
    Surgical techniques for right hemicolectomy (RHC) show considerable heterogeneity. To identify potential areas for improvement and standardization, the objective of this survey was to evaluate and report current practices and preferences among surgeons for performing RHC for colorectal cancer. An international online survey consisting of 31 questions was distributed to general surgeons worldwide to assess their preferred techniques for performing RHC. A total of 368 surgeons from 48 countries responded. Among them, 47% reported performing at least 90% of RHC laparoscopically, while 40% used a robotic approach. The most common dissection technique was a medial-to-lateral vessel-first approach, used by 82.3% of respondents. During laparoscopic procedures, 51.6% of surgeons performed extracorporeal anastomosis, whereas 82.9% of those using a robotic approach favored intracorporeal anastomosis. Fluorescence angiography was routinely used by 39.9% of respondents. The Pfannenstiel incision was the most frequently selected extraction site (46.5%) especially if intracorporeal anastomosis was performed (81.8%). The preferred technique for performing RHC includes a laparoscopic approach with intracorporeal lymph node dissection and extracorporeal anastomosis. Most RHC procedures therefore remain laparoscopy-assisted rather than fully minimally invasive. Robotic surgery appears to facilitate a fully minimally invasive approach including intracorporeal anastomosis.
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    Procalcitonin-Informed decision-making in abdominal and emergency surgery: A WSES position paper
    (2026) Catena, Fausto; De Simone, B.; Kryvoruchko, Ihor; Di Saverio, Salomone; Ribeiro, Marcelo; Hardcastle, Timothy Craig; Isık, Arda; Ioannidis, Orestis; Podda, Mauro; Di Martino, Marcello
    Background: Procalcitonin (PCT) may support decision-making in abdominal and emergency surgery when infection is difficult to distinguish from non-infectious inflammation. Its interpretation remains challenging because clinical settings, sampling schedules, and proposed thresholds vary. This WSES position paper examines the evidence across six clinical scenarios to provide a practical framework for PCT-informed decision-making. Methods: A structured literature review covering January 1980 to December 2025, with targeted updates through August 2026, informed six PICO-based clinical questions. Evidence appraisal drew on selected GRADE domains, including consistency, directness, and precision. Recommendations were developed through iterative expert review and consensus. Results: The panel formulated six conditional recommendations addressing intra-abdominal infection diagnosis, antibiotic discontinuation after source control, suspected source-control failure, infected pancreatic necrosis, infectious complications after trauma, and postoperative anastomotic leak. The panel’s qualitative assessment rated evidence certainty as moderate for antibiotic discontinuation and the pancreatitis domain, and low for the remaining domains. Serial PCT trends may complement clinical assessment in selected patients. Evidence for reduced antibiotic exposure with predefined PCT algorithms is more established than evidence that PCT-informed imaging, reintervention, or discharge decisions improve patient outcomes. Conclusions: PCT-informed decision-making in abdominal surgery may contribute to a more individualized approach to emergency surgical care and precision emergency surgery. When interpreted as part of serial assessment and integrated with clinical judgement, organ-dysfunction trends, microbiology, imaging, and evaluation of source-control adequacy, PCT may support individualized antibiotic discontinuation, potentially earlier recognition of an unfavourable clinical course, and more timely diagnostic and source-control reassessment. Current evidence does not support universal thresholds or routine serial testing in all surgical patients. Biomarker kinetics should strengthen, but not replace, surgical reasoning or independently determine antimicrobial, imaging, or interventional decisions. Future research should validate setting-specific thresholds and sampling schedules, establish whether PCT provides actionable information before clinical deterioration, and evaluate the clinical effects and cost-effectiveness of PCT-informed pathways.