Кафедра дитячої хірургії та дитячої анестезіології
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Browsing Кафедра дитячої хірургії та дитячої анестезіології by Author "Mishyna, Maryna"
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Item Daily biorhythms of biofilm formation by pathogens of inflammatory diseases in children and influence on them by ultrasonic and ozone(2020-02-24) Davidenko, Vyacheslav; Mishyna, Maryna; Roy, N.V.; Romanova, N.V.Treatment of severe purulent diseases in children is associated with high resistance of microbes. One of the most significant antibiotic resistance factors is the ability of pathogenic microbes to form biofilms. In a state of biofilm, microbes increase their resistance by 500 to 10,000 times. During this period, they are practically not affected by antimicrobial agents. In this regard, methods for the destructive effect on biofilms are important for successful treatmentItem Drug Resistance of Purulent-Inflammatory Diseases Pathogensin Children and Ways to Overcome it(2018-11-16) Давиденко, Вячеслав Борисович; Пащенко, Юрій Володимирович; Мішина, Марина Митрофанівна; Рой, Наталя Вячеславівна; Davidenko, Vyacheslav; Pashchenco, Yu.; Mishyna, Maryna; Roi, N.Modern pathogenic microorganisms have pronounced drug resistance to antimicrobial drugs. This significantly reduces the effectiveness of treatment of purulent inflammatory diseases in children. The stability of microorganisms is due to biofilm formation and various factors of aggression. Hence, scientific research is necessary to eliminate microbial resistance and increase effectiveness of antimicrobial therapy.Item Estimation of growth kinetics daily dynamics and pathogenicity factors of microorganisms – causative agents of peritonitis in children.(2019-05-31) Davidenko, Vyacheslav; Pashchenko, Yurii; Roy, Natalya; Mishyna, Maryna; Marchenko, I.; Mozgova, Yu.Item Modern methods of treatment of inflammatory surgical diseases in children(2019-04-26) Davidenko, Vyacheslav; Roi, N.V.; Mishyna, MarynaModern pathogenic microorganisms have a pronounced drug resistance to antimicrobial drugs. This significantly reduces the effectiveness of treatment of purulent-inflammatory diseases in children. The stability of microorganisms is due to biofilm formation and various factors of aggression. So scientific research is necessary to eliminate microbial resistance and increase the effectiveness of antimicrobial therapy.Item Networks of neutrophil extracellular traps in anti-microbial treatment of purulent inflammatory diseases in children.(2019-10-04) Davidenko, Vyacheslav; Mishyna, Maryna; Piontkovskaya, Piontkovskaya; Roy, NataliaMicroflora of purul ent inflammatory diseases in children has a pronounced resistance to antimicrobial agents. Improving treatment results is associated with the development and implementation of modern effective treatment methods. The teams of the departments of pediatric su rgery and microbiology of KhNMU studied such treatment methods as ultrasonic cavitation, ozon therapy, antibiotic therapy taking into account daily microbial biorhythms, the role of extracellular traps in phagocytosis.Item The effect of low-intensity ultrasound in combination with antimicrobial agents on biofilms of the pathogens of pyo-inflammatory diseases in children(Seoul National University Press, 2016-06) Давиденко, Вячеслав Борисович; Мішина, Марина Митрофанівна; М'ясоєдов, Валерій Васильович; Штикер, Станіслав Юрійович; Пащенко, Юрій Володимирович; Давиденко, Наталія Вячеславівна; Мішин, Юрій Миколайович; Davidenko, Vyacheslav; Mishyna, Maryna; Myasoedov, V.; Shtyker, S.; Pashchenko, Yu.; Davidenko, N.; Mishyn, YuriyThere was investigated the combined influence of low-intensity ultrasound and antimicrobials on biofilms of clinical strains of E. coli and S. aureus to assess the degree of disruption of daily biofilms, and to study their ability to produce plankton cells as a factor of dissemination of the pathogen. The breach of the integrity of daily biofilms of clinical strains of E. coli and S. aureus and decreased ability of the plankton cells production after the action of low-intensity ultrasound within 10-min processing combined with application of antimicrobial agents were determined. It was shown that only the action of low-intensity ultrasound during 10 min with subsequent use of antimicrobials led to the complete inactivation of plankton cells and disorganization of the biofilm of E. coli and S. aureus isolates.