Кафедра дитячої хірургії та дитячої анестезіології
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Item Changes in the level of interleukin-4 and interleukin-6 in response to angioproteCtive therapy in Children with severe birth asphyxia(2020) Danylova, Viktoria; Ovcharenko, Sergey; Kalnytska, ViolettaThe development of clinical and laboratory criteria for diagnosis of systemic inflammatory response significantly expanded the use of this concept in clinical practice. The correlation between the levels of antiinflammatory and pro-inflammatory cytokines is an important aspect in regulation of systemic inflammatory response. Treatment of systemic inflammatory response includes three main links: effect on the levels of endotoxin, cytokines and the state of endothelium. Currently there is no unified approach to the solution of this problem, which determines the relevance of the topic. The aim of the research was to study the efficacy of the deproteinized hemodialysate from the newborn calf blood in systemic inflammatory response in newborns with severe asphyxia at birth.Item Combined treatment of hemangiomas(2018) Вівчарук, Вікторія Петрівна; Пащенко, Юрій Володимирович; Pashchenko, Yu.V.; Vivcharuk, V.P.Infantile hemangioma is a benign vascular tumor in young children with a characteristic life cycle (proliferative, involutive phases), which is also a unique model of postnatal vasculogenesis, angiogenesis and vascular regression. Tumor growth is conditioned by the influence of pro-angiogenic factors. Considerable part of complications develops precisely in the proliferation phase. A rapid increase in hemangiomas is an indication for treatment, which should be based on the age of the patient, localization, size and aggressiveness of the growth.Item Daily biorhythms of biofilm formation by pathogens of inflammatory diseases in children and influence on them by ultrasonic and ozone(2020-02-24) Davidenko, Vyacheslav; Mishyna, Maryna; Roy, N.V.; Romanova, N.V.Treatment of severe purulent diseases in children is associated with high resistance of microbes. One of the most significant antibiotic resistance factors is the ability of pathogenic microbes to form biofilms. In a state of biofilm, microbes increase their resistance by 500 to 10,000 times. During this period, they are practically not affected by antimicrobial agents. In this regard, methods for the destructive effect on biofilms are important for successful treatmentItem Drug Resistance of Purulent-Inflammatory Diseases Pathogensin Children and Ways to Overcome it(2018-11-16) Давиденко, Вячеслав Борисович; Пащенко, Юрій Володимирович; Мішина, Марина Митрофанівна; Рой, Наталя Вячеславівна; Davidenko, Vyacheslav; Pashchenco, Yu.; Mishyna, Maryna; Roi, N.Modern pathogenic microorganisms have pronounced drug resistance to antimicrobial drugs. This significantly reduces the effectiveness of treatment of purulent inflammatory diseases in children. The stability of microorganisms is due to biofilm formation and various factors of aggression. Hence, scientific research is necessary to eliminate microbial resistance and increase effectiveness of antimicrobial therapy.Item Early diagnostic and surgical correction of cjngenital hydronephrosis in children(2020-01-08) Davidenko, Vyacheslav; Grechanina, Elena; Lapshin, Vyacheslav; Roy, N.; Mayboroda, T.Congenital hydronephrosis in children makes up a significant part of all abnormalities and malformations. The reasons for the development of hydronephrosis are such organic abnormalities as hypoplasia of the pylorourethral segment, high ureteral discharge and the presence of an aberrant vessel compressing the ureter.Item Estimation of growth kinetics daily dynamics and pathogenicity factors of microorganisms – causative agents of peritonitis in children.(2019-05-31) Davidenko, Vyacheslav; Pashchenko, Yurii; Roy, Natalya; Mishyna, Maryna; Marchenko, I.; Mozgova, Yu.Item Etiological Structure and Antibiotic Resistance of Nosocomial Pneumonia Pathogens in Children in ICUs(Kyiv, 2018-11-16) Данилова, Вікторія Василівна; Колісник, А.М.; Стародуб, А.С.; Danilova, V.; Kolisnik, A.; Starodub, A.Antibiotic therapy policy can influence not only the frequency of infectious complications, but also the main results of treatment in the most difficult to treat contingent of patients in intensive care units (ICU). Bacterial infections are the most common complication in patients of intensive care units. In recent years, practical possibilities of antimicrobial therapy have expanded significantly with the advent of new, highly effective antibacterial agents. On the other hand, infection is a complex, dynamic process caused by interaction of microorganisms and a macroorganism, which explains the lack of universal guidelines for the treatment of postoperative complications in patients in ICU. The incidence of infectious complications increases significantly along with an increase in length of stay of patients in intensive care units.Item Experiecne of the clinic in the treatment of acute destructive pneumonia in children(Accent Graphics Communications & Publishing, 2019-02-01) Roi, N.; Knyhin, M.Acute Destructive Pneumonia remains severe purulent disease in children. This disease is characterized by a variety of clinical forms and complications. Etiological microflora has a high polymorphic resistance to the vast majority of antibacterial agents, which greatly complicates the treatment. Our goal was to study modern highly effective methods of treatment of Acute Destructive Pneumonia and to apply in practice for treating children with Acute Destructive Pneumonia.Item Experience of tien application in neonatal reanimatology(2019-02-28) Danilova, V.; Kolisnyk, A.Treatment of purulent-septic diseases in newborns is an actual problem of pediatrics in general and neonatal, in particular, since purulent-septic processes in newborns remain the leading cause of death in this cohort of patients. In addition, in neonatology, as nowhere else, there is the problem of hospital infection and the real fight against it.Item Features of the current and treatment of the hemolitical-uremic syndrome (clinical pracrice case)(2019-01-01) Danilova, V.; Kolosnyk, A.Hemolytic-uremic syndrome in young children as the most common cause of acute renal failure, as well as the source of the formation of chronic kidney disease in subsequent years, is still a current problem.Item Formation of scientific potential of the Kharkiv national medical university in the context of the development of the national economy(ЧНТУ, 2018-11-09) Syrova, Ganna; Lukianova, Larysa; Lapshin, VyacheslavAn important factor in the formation of the innovative potential of the economy is the activities of scientific organizations, in particular, academic institutions. This is due to the fact that, unlike countries where scientific research is carried out mainly by universities, our state inherited from the former Soviet Union a system based on scientific institutions of the academies of sciences. The question of the formation of the country's innovation development, the place of academies of sciences in the innovation process was regulated by the newly adopted wording of the Law of Ukraine "On Scientific and Scientific and Technical Activity". The problem of constant growth of the economy on the basis of its transition to an innovative way of development is widely researched by domestic economic science.Item Intestinal anastomosis with high risk of leakage(2018-09-07) Пащенко, Юрій Володимирович; Пащенко, Костянтин Юрійович; Вівчарук, Вікторія Петрівна; Pashchenko, Yu.V.; Pashchenko, K.Yu.; Vivcharuk, V.Performing of intestinal anastomoses in newborns and young children with multiple atresia, thrombohemorrhagic processes and infection of abdominal cavity can be complicated with anastomoses failure.Item Management of blunt and penetrating abdominal trauma in children(2014-12-25) Shtyker, StanislavThe lecture is devoted to clinical features, diagnosis and treatment of blunt and penetrating abdominal trauma in childrenItem Modern medical complex for the treatment of acute destructive pneumonia in children(2019-03-29) Roi, Natalya; Bevz, SergiyBackground: Acute destructive pneumonia is the most common severe inflammatory disease in children. In the treatment of this disease, there are problems associated with the presence of a high degree of drug resistance of the etiological microflora and the development of severe hemodynamic and respiratory disorders. Antibacterial therapy is pathogenically justified in the treatment of ADP. Impact on a macro-organism includes detoxification therapy, immunomodulation, oxygenotherapy and symptomatic therapyItem Modern methods of treatment of inflammatory surgical diseases in children(2019-04-26) Davidenko, Vyacheslav; Roi, N.V.; Mishyna, MarynaModern pathogenic microorganisms have a pronounced drug resistance to antimicrobial drugs. This significantly reduces the effectiveness of treatment of purulent-inflammatory diseases in children. The stability of microorganisms is due to biofilm formation and various factors of aggression. So scientific research is necessary to eliminate microbial resistance and increase the effectiveness of antimicrobial therapy.Item Networks of neutrophil extracellular traps in anti-microbial treatment of purulent inflammatory diseases in children.(2019-10-04) Davidenko, Vyacheslav; Mishyna, Maryna; Piontkovskaya, Piontkovskaya; Roy, NataliaMicroflora of purul ent inflammatory diseases in children has a pronounced resistance to antimicrobial agents. Improving treatment results is associated with the development and implementation of modern effective treatment methods. The teams of the departments of pediatric su rgery and microbiology of KhNMU studied such treatment methods as ultrasonic cavitation, ozon therapy, antibiotic therapy taking into account daily microbial biorhythms, the role of extracellular traps in phagocytosis.Item Pediatric Surgery : textbook for medical students(2011) Davidenko, Vyacheslav; Shtyker, Stanislav; Belopaschentcev, Vladislav; Paschenko, Yuriy; Vjun, ValeriyIn the textbook the essential parts of pediatric surgery, which are required for the training of general practitioners, are represented. The main attention is devoted to the clinical manifestation, diagnostics and algorithms of the treatment optimization for the most common and characteristic surgical pathology in childhood. The newest, up-to-date achievements in the surgery of malformations in children are illustrated. Novel advancing fields such as pediatric laparoscopy and fetal surgery are depicted briefly. The contents of the book correspond to the extent of the standard program on pediatric surgery for the higher medical institutes of III-IV levels of accreditation and recommended mainly for the foreign English-speaking medical students of 5-6th courses.Item Pediatrics acute hematogenous osteomyelits(2019-04-13) Thuraya, Ismail Al-Bhaisi; Vivcharuk, Victoria; Pashchenko, Konstantin; Shtyker, StanislavOsteomyelitis is a bacterial inflammation of bones, it mostly affects long bones. It occurs when the bacterium travels from its original site to the bone. It is more common in children because there is higher blood circulation in bones which provides necessary nutrition for their growth.Item The effect of low-intensity ultrasound in combination with antimicrobial agents on biofilms of the pathogens of pyo-inflammatory diseases in children(Seoul National University Press, 2016-06) Давиденко, Вячеслав Борисович; Мішина, Марина Митрофанівна; М'ясоєдов, Валерій Васильович; Штикер, Станіслав Юрійович; Пащенко, Юрій Володимирович; Давиденко, Наталія Вячеславівна; Мішин, Юрій Миколайович; Davidenko, Vyacheslav; Mishyna, Maryna; Myasoedov, V.; Shtyker, S.; Pashchenko, Yu.; Davidenko, N.; Mishyn, YuriyThere was investigated the combined influence of low-intensity ultrasound and antimicrobials on biofilms of clinical strains of E. coli and S. aureus to assess the degree of disruption of daily biofilms, and to study their ability to produce plankton cells as a factor of dissemination of the pathogen. The breach of the integrity of daily biofilms of clinical strains of E. coli and S. aureus and decreased ability of the plankton cells production after the action of low-intensity ultrasound within 10-min processing combined with application of antimicrobial agents were determined. It was shown that only the action of low-intensity ultrasound during 10 min with subsequent use of antimicrobials led to the complete inactivation of plankton cells and disorganization of the biofilm of E. coli and S. aureus isolates.Item Transanal penetrating injuries to the colon in children(2018-09-07) Басілайшвілі, Юрій Валентинович; Сігаєв, Борис Євгеньович; Штикер, Станіслав Юрійович; Basylaishvili, Yu.; Sihaev, B.; Shtyker, S.Traumatic injuries of the anorectal zone in children are rare. There are very few reports on this subject in the literature. Meanwhile, a pediatric surgeon can meet with wounds of the rectum penetrating into the abdominal cavity, which are extremely severe. Among all abdominal organs rectal injuries account for 1 - 5%, increasing the frequency up to 6,6% in fractures of the pelvis and to 19 % in gluteal region wounds. The rarest group of injuries to the colon is transanal wounds of the rectum, penetrating into the abdominal cavity without the perineal wound.