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The influence of a-lipoic acid to endothelial dysfunction and adipokines balance in patients with type 2 diabetes and essential hypertension in the presence of unfavorable genetic polymorphism

Abstract

A/C and C/C genotypes of AGTR1, Pro/Pro genotype of PPARg2, Arg/Arg and Gly/Arg genotypes of IRS-1, T/T and C/T genotypes of TCF7L2 are associated with the development of comorbidity of DM2 and EH. The additional a-LC appointment to standard therapy impacted more to the severity of ED and adypokines balance than basic therapy.

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Citation

Shalimova A. The influence of a-lipoic acid to endothelial dysfunction and adipokines balance in patients with type 2 diabetes and essential hypertension in the presence of unfavorable genetic polymorphism / A. Shalimova, A. Belovol, L. Bobronnikova, M. Kochueva, V. Рsareva, N. Kirichenko // 18th European Congress of Endocrinology, Munich, Germany, 28–31 May 2016 : Endocrine Abstracts. – 2016. – Vol. 41. – P. 305.

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