Relationship between vaspin and carotid intima media thickness in patients with diabetes type 2

Abstract

Carotid intima-media thickness (C-IMT) is a surrogate marker of subclinical atherosclerosis that is measured to prevent cardiovascular disease. Type 2 Diabetes Mellitus (T2DM) is a significant risk factor for cardiovascular events development. It is well known that a lot of adipocytokines can be involved into regulation of metabolic processes and inflammatory response. Both of these processes take part in atherosclerosis development. Vaspin is a molecule belonging to adipokine family which is associated with insulin resistance and obesity in humans. However, the relationship between serum vaspin levels and atherosclerosis remains unknown.