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http://repo.knmu.edu.ua/handle/123456789/20744| Title: | Estimation of mortality prognosis in patients with acute myocardial infarction and type 2 diabetes mellitus taking into account intercellular matrix parameters |
| Authors: | Котелюх, Марія Юріївна Кравчун, Павло Григорович Борзова, Олена Юріївна Ринчак, Петро Іванович Журавльова, Марина Ігорівна Koteliukh, Mariia Kravchun, Pavlo H. Borzova, Olena Rynchak, Petro Zhuravleva, M. |
| Keywords: | acute myocardial infarction matrix metalloproteinase-13 extracellular matrix tissue inhibitor of metalloproteinase-4 type 2 diabetes mellitus |
| Issue Date: | 2018 |
| Citation: | Estimation of mortality prognosis in patients with acute myocardial infarction and type 2 diabetes mellitus taking into account intercellular matrix parameters / M. Yu. Koteliukh, P. G. Kravchun, O. Yu. Borzova, P. I. Rynchak, M. I. Zhuravleva // Science Review. – 2018. – № 1 (8). – С. 45–50. |
| Abstract: | Ischemic heart disease ranks first among cardiovascular disorders and is one of the main causes of disability and mortality worldwide. The development and course of acute myocardial infarction is known to be accompanied by changes in extracellular matrix. Today the impact of hyperglycemia on intercellular matrix system in patients with acute myocardial infarction and type 2 diabetes still remains disputable. The study demonstrated a statistically significant increase in matrix metalloproteinase-13 in an insufficient increase in the level of tissue inhibitor of metalloproteinase-4 in patients with acute myocardial infarction and type 2 diabetes, indicating an imbalance in intercellular matrix system. The authors defined prognostic characteristics regarding matrix metalloproteinase-13 and tissue inhibitor of metalloproteinase-4 in patients with acute myocardial infarction and type 2 diabetes as for mortality of these patients. |
| URI: | https://repo.knmu.edu.ua/handle/123456789/20744 |
| Appears in Collections: | Наукові праці. Кафедра внутрішньої медицини № 2 і клінічної імунології та алергології ім. ак. Л.Т. Малої |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| ESTIMATION OF MORTALITY PROGNOSIS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AND TYPE 2 DIABETES MELLITUS TAKING INTO ACCOUNT INTERCELLULAR MATRIX PARAMETERS.docx | 19,63 kB | Microsoft Word XML | View/Open |
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