The influence of phosphorus complex organic mixtures on the content of sexual hormones and gonadotropins in the serum with violations in the reproductive system
Date
2017-12
Authors
Жарова, Наталія Валентинівна
Багмут, Ірина Юріївна
Тіткова, Анна Володимирівна
Маракушин, Дмитро Ігорович
Резуненко, Юрій Костянтинович
Zharova, Nataliya
Bagmut, Irina
Titkova, Anna
Marakushyn, Dmytro
Rezunenko, Yu.
Journal Title
Journal ISSN
Volume Title
Publisher
Oxford university press
Abstract
At 100 Wistar rat population in subacute experiment the effect of
small doses of subtoxical phosphorus detergents (Efasol, Polifos, Syntaf) on the level
of sex hormones in the blood serum of females - estrogen and gonadotropins was
investigated by radioimmunoassay. There were 9 research groups and one control,
10 animals in each (N=100). Estrogen and gonadotropins were studied in rat serum.
Significant inhibition of gonadotropin secretion may be combined with the
permeability of the haemato-encefalic barrier for phosphorus complex organic
compounds and their direct influence on the hypothalamic-pituitary neuroendocrine
complex.
Description
Keywords
xenobiotics, progesteron, prolactin, luteotropin, follicle-stimulating hormone, estradiol, serum, rats
Citation
The influence of phosphorus complex organic mixtures on the content of sexual hormones and gonadotropins in the serum with violations in the reproductive system / N. V. Zharova, I. Yu. Bagmut, A. V. Titkova, D. I. Marakushyn, Yu. K. Rezunenko // The journal of medicine and philosophy. – 2017. – Issue 6 (2), vol. 42. – Р. 1306–1311.