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http://repo.knmu.edu.ua/handle/123456789/13639| Title: | Structural functional parameters of the heart in patients with coronary heart disease with concomitant obesity depending on genotypes of gene of tumor necrosis factor-α (G-308A) |
| Authors: | Кравчун, Павло Григорович Кадикова, Ольга Ігорівна Риндіна, Наталія Геннадіївна Крапівко, Світлана Олександрівна Молотягін, Дмитро Геннадійович Kravchun, Pavlo H. Kadykova, Olga Ryndina, Natalia Krapivko, Svitlana Molotyahin, Dmytro |
| Keywords: | polymorphism gene of tumor necrosis factor-α coronary heart disease obesity |
| Issue Date: | 2016 |
| Citation: | Structural functional parameters of the heart in patients with coronary heart disease with concomitant obesity depending on genotypes of gene of tumor necrosis factor-α (G-308A) / P. G. Kravchun, O. I. Kadykova, N. G. Ryndina, S. O. Krapivko, D. G. Molotiagin // British Journal of Educational and Scientiic Studies. – 2016. – Vol. 12, № 1 (23), January–June. – P. 864–871. |
| Abstract: | The article deals with influence of different genotypes of gene of tumor necrosis factor-α on changes of structure and function of the myocardium in patients with coronary heart disease with concomitant obesity by means of examination of 222 patients. Conclusions. In patients with coronary heart disease (CHD) and obesity with genotype A/A of TNF-α gene (G-308A) more significant disorders in structure and function of the myocardium are observed, that is increased dimensions of the left ventricle, its mass associated with reduced contraction ability, which results in unfavorable left ventricle remodeling and development of diastolic dysfunction of the left ventricle. |
| URI: | https://repo.knmu.edu.ua/handle/123456789/13639 |
| Appears in Collections: | Наукові праці. Кафедра внутрішньої медицини № 2 і клінічної імунології та алергології ім. ак. Л.Т. Малої |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Кадикова в British Journal.doc | 265 kB | Microsoft Word | View/Open |
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