Structural functional parameters of the heart in patients with coronary heart disease with concomitant obesity depending on genotypes of gene of tumor necrosis factor-α (G-308A)

dc.contributor.authorКравчун, Павло Григорович
dc.contributor.authorКадикова, Ольга Ігорівна
dc.contributor.authorРиндіна, Наталія Геннадіївна
dc.contributor.authorКрапівко, Світлана Олександрівна
dc.contributor.authorМолотягін, Дмитро Геннадійович
dc.contributor.authorKravchun, Pavlo H.
dc.contributor.authorKadykova, Olga
dc.contributor.authorRyndina, Natalia
dc.contributor.authorKrapivko, Svitlana
dc.contributor.authorMolotyahin, Dmytro
dc.date.accessioned2016-08-29T13:20:56Z
dc.date.available2016-08-29T13:20:56Z
dc.date.issued2016
dc.description.abstractThe article deals with influence of different genotypes of gene of tumor necrosis factor-α on changes of structure and function of the myocardium in patients with coronary heart disease with concomitant obesity by means of examination of 222 patients. Conclusions. In patients with coronary heart disease (CHD) and obesity with genotype A/A of TNF-α gene (G-308A) more significant disorders in structure and function of the myocardium are observed, that is increased dimensions of the left ventricle, its mass associated with reduced contraction ability, which results in unfavorable left ventricle remodeling and development of diastolic dysfunction of the left ventricle.ru_RU
dc.identifier.citationStructural functional parameters of the heart in patients with coronary heart disease with concomitant obesity depending on genotypes of gene of tumor necrosis factor-α (G-308A) / P. G. Kravchun, O. I. Kadykova, N. G. Ryndina, S. O. Krapivko, D. G. Molotiagin // British Journal of Educational and Scientiic Studies. – 2016. – Vol. 12, № 1 (23), January–June. – P. 864–871.ru_RU
dc.identifier.urihttps://repo.knmu.edu.ua/handle/123456789/13639
dc.language.isoenru_RU
dc.subjectpolymorphismru_RU
dc.subjectgene of tumor necrosis factor-αru_RU
dc.subjectcoronary heart diseaseru_RU
dc.subjectobesityru_RU
dc.titleStructural functional parameters of the heart in patients with coronary heart disease with concomitant obesity depending on genotypes of gene of tumor necrosis factor-α (G-308A)ru_RU
dc.typeArticleru_RU

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