The effect of phosphorus organic mixtures on chromosome aberration and cells’ mitotic activity of red bone marrow in the subacute experiment
dc.contributor.author | Bagmut, Irina | |
dc.contributor.author | Zharova, Nataliya | |
dc.contributor.author | Titkova, Anna | |
dc.contributor.author | Boiagina, Olga | |
dc.contributor.author | Rezunenko, Yu. | |
dc.contributor.author | Боягіна, Ольга Дмитрівна | |
dc.contributor.author | Жарова, Наталія Валентинівна | |
dc.contributor.author | Тіткова, Анна Володимирівна | |
dc.contributor.author | Багмут, Ірина Юріївна | |
dc.contributor.author | Резуненко, Юрій Костянтинович | |
dc.date.accessioned | 2017-11-14T13:24:10Z | |
dc.date.available | 2017-11-14T13:24:10Z | |
dc.date.issued | 2017-12 | |
dc.description.abstract | At 100 Wistar rats population in subacute experiment the effect of small sub-toxic doses of phosphorus detergents (Efasol, Polifos, Syntaf) on the level of chromosomal aberrations and cells' mitotic activity of red bone marrow was investigated. There were 9 research groups of animals and one control in certain clear relationship between dose intensity and toxic effects of restructuring chromosomal apparatus. The number of cells with chromosomal aberrations in a dose-dependent (1/10, 1/100 LD50) increased from 5 to 10 times. The study of cells' mitotic activity of red bone marrow identified reducing mitotic index, which may indicate the cytostatic effect of phosphorus detergents in appropriate doses 1/10 and 1/100 LD50. All xenobiotics in 1/1000 LD50 dose did not affect the genetic apparatus of male rats. | ru_RU |
dc.identifier.citation | The effect of phosphorus organic mixtures on chromosome aberration and cells’ mitotic activity of red bone marrow in the subacute experiment / I. Yu. Bagmut, N. V. Zharova, A. V. Titkova, O. D. Boiagina, Yu. K. Rezunenko // The quarterly review of biology. – 2017. – Issue 4 (2), vol. 92. – Р. 701–705. | ru_RU |
dc.identifier.issn | 0033-5770 | |
dc.identifier.uri | https://repo.knmu.edu.ua/handle/123456789/18157 | |
dc.language.iso | en | ru_RU |
dc.subject | xenobiotics | ru_RU |
dc.subject | phosphorus | ru_RU |
dc.subject | detergents | ru_RU |
dc.subject | cells' mitotic activiy | ru_RU |
dc.subject | red bone marrow | ru_RU |
dc.subject | rats | ru_RU |
dc.title | The effect of phosphorus organic mixtures on chromosome aberration and cells’ mitotic activity of red bone marrow in the subacute experiment | ru_RU |
dc.type | Article | ru_RU |
Files
Original bundle
1 - 1 of 1
- Name:
- 02_The effect of phosphorus organic mixtures on chromosome aberration and cells’ mitotic activity of red bone marrow in the subacute experiment.pdf
- Size:
- 514 KB
- Format:
- Adobe Portable Document Format
License bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- license.txt
- Size:
- 11.51 KB
- Format:
- Item-specific license agreed upon to submission
- Description: