An impact of compounds of imidazoline on speed of oxygen intake by mitochondria of rats’ hepatocyte

Abstract

A main problem of modern medicine is revelation of biochemical mechanisms of pathological processes development during impact on xenobiotics organism (XO). Compounds of imidazoline are compounds of xenobiotics organism components of which according to physical and chemical peculiarities and molecules structure properties contain group of cationic surface active substances. Compounds of imidazoline are characterized by significant synthesis volume, wide use in different fields of economic and intake in water sources and possible impact on population health. Previous investigations determined long-lasting rats’ toxification by compounds of imidazoline with alkyl radicals S7-9 and S9-15 in doses 1/10 and 1/100 DL50 initiates the development of oxidative stress with the destruction of protein and lipid molecule. Aim of the work was to study the speed of oxygen intake by mitochondria of rats’ hepatocytes on the 30th day of compounds of imidazoline impact in dose 1/100 DL 50.