The adipokin visfatin insulin sensitivity, inflammation regulator in patients with hypertension and obesity

Abstract

Adipokines play a significant role in the pathogenesis of a lowgrade inflammation associated with obesity, metabolic syndrome and in chronic inflammatory. Visfatin is a novel adipocytokine identified in 2005. On the other hand, visfatin has been suggested to be a beneficial adipokine with insulinmimicking- sensitizing effects, but regulation of visfatin production and its physiological importance in the conditions of obesity and type 2 diabetes mellitus are still not completely understood.