Relationship between adiponectin and anthropometric parameters, insulin resistance and transaminase levels in patients with nonalcoholic fatty liver disease and type 2 diabetes mellitus

Abstract

The basis of the pathogenesis of nonalcoholic fatty liver disease (NAFLD) is insulin resistance (IR) which appears on the background of abdominal obesity (AO) which, in turn, is a key factor in the emergence of an imbalance between adipocytokines entailing a violation of lipid and carbohydrate metabolism, which ultimately leads to the damage of the liver cells, the development of inflammation, fibrosis and apoptosis.