Active persistence of the epstein-barr virus worse prognosis esophagits in school children
dc.contributor.author | Pavlenko, Nataliia | |
dc.contributor.author | Павленко, Наталія Володимирівна | |
dc.contributor.author | Belousova, Olga | |
dc.contributor.author | Бєлоусова, Ольга Юріївна | |
dc.contributor.author | Solodovnichenko, Irina | |
dc.contributor.author | Солодовниченко, Ірина Григорівна | |
dc.contributor.author | Voloshyn, K. V. | |
dc.contributor.author | Волошин, К. В. | |
dc.contributor.author | Babadzhanyan, Olena | |
dc.contributor.author | Бабаджанян, Олена Миколаївна | |
dc.contributor.author | Shutova, Olena | |
dc.contributor.author | Шутова, Олена Валентинівна | |
dc.contributor.author | Voloshyna, Lidiia | |
dc.contributor.author | Волошина, Лідія Георгіївна | |
dc.contributor.author | Hanzii, Olena | |
dc.contributor.author | Ганзій, Олена Богданівна | |
dc.date.accessioned | 2024-05-14T13:34:20Z | |
dc.date.available | 2024-05-14T13:34:20Z | |
dc.date.issued | 2023 | |
dc.description.abstract | Aims: To study the effect of active persistence of EBV in school-age children with esophagitis and complicated variants of GERD, based on the results of a comprehensive study. Methods: 388 children aged 6-18 years with esophagitis were examined. The diagnosis was verified endoscopically and morphologically. Hр was determined histologically, the activity of EBV - by PCR of blood serum. The results were statistically processed. Results: The overall infection with Hp was 56%. Patients were divided into 2 groups: group 1 - 295 (76%) patients with catarrhal esophagitis, group 2 - 93 (24%) patients with erosive esophagitis. EBV in catarrhal esophagitis was detected in 12%, and in erosive esophagitis in 48% of patients (p<0.01). 24.5% of patients with erosive esophagitis had complications in the form of torpid slit-like erosions, ulcers and polyps of the esophagus. When analyzing the infection rate of this category of patients, it turned out that Hp-positive variants of complicated esophagitis accounted for only 28%, while active EBV infection was detected in 92% of patients (p<0.01). Conclusions: EBV is significantly more often detected in school-age children with erosive and complicated esophagitis. Active long-term persistence of EBV worsens the prognosis of esophagitis. | en_US |
dc.identifier.citation | Active persistence of the epstein-barr virus worse prognosis esophagits in school children / N. V. Pavlenko, O. Yu. Belousova, I. G. Solodovnichenko, K. V. Voloshin, O. M. Babadzhanian, O. V. Shutova, L. G. Voloshina, O. B. Hanzii // of The World Society for Pediatric Infectious Diseases (WSPID23) : 13th World Congress, Durban, South Africa, 14─17 November 2023 : Abstract book / World Society for Pediatric Infectious Diseases. – Durban, 2023. – P. 372. | en_US |
dc.identifier.uri | https://repo.knmu.edu.ua/handle/123456789/33762 | |
dc.language.iso | en_US | en_US |
dc.publisher | World Society for Pediatric Infectious Diseases | en_US |
dc.subject | active EBV infection | en_US |
dc.subject | esophagitis | en_US |
dc.subject | school-age children | en_US |
dc.subject | 2024а/2023 | en_US |
dc.title | Active persistence of the epstein-barr virus worse prognosis esophagits in school children | en_US |
dc.title.alternative | Активна персистенція вірусу Епштейн-Барр погіршує прогноз езофагітів у дітей шкільного віку | en_US |
dc.type | Thesis | en_US |
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