Modern trends in the formation of comorbid pathology of the esophagus and gastroduodenal zone in children

Abstract

The article presents modern views on trends and controversial issues in the formation of combined pathology of the gastroduodenal zone and esophagus in children. The purpose of the authors of this study: to identify the features of the formation, course and outcomes of gastroesophageal reflux disease (GERD) in children with pathology of the gastroduodenal zone (GDZ) based on endoscopic and morphological comparisons. Own long-term observations were analyzed depending on the type of pathology, the severity of motor disorders, endoscopic and morphological picture, infection Helicobacter pylori. Possible options for the formation of gastroesophageal reflux disease in children and adolescents with various diseases of the gastroduodenal zone were determined. It has been established that the combined nature of the pathology of the esophagus and gastroduodenal zone in children occurs in more than 75% of patients. The nature and severity of esophageal disorders depend on the nature of the nosology of the gastroduodenal zone and, as a rule, are secondary. The increase in the frequency of GERD in modern children, the increase in the proportion of its complicated variants (including ulcers and Barrett's esophagus), make it a priority in the study of diseases of the upper digestive tract in children at the present time. For this contingent of young patients, it is urgent and urgent to develop clear diagnostic criteria (including endoscopic and morphological criteria), therapy tactics, and a strategy for cancer prevention.