Functional hybrid organo-inorganic composite materials of the incorporative type for the recovery of articular cartilage defects

Abstract

The concept of obtaining a functional hybrid organo-inorganic composite material of the incorporation type with a binder based on polyacrylic acid and a nanocrystalline filler of a fragmentary structure has been developed. Ca3(PO4)2 particles contain two phases with a semicoherent boundary between them. Structuring of the composite takes place at five levels: in the volume of the polymer binder, in the interfacial layer and the polymer matrix adjacent to it, and in the outer and inner layers of the calcium phosphate filler. The effects of composition, structure, and the ratio of the initial components on the properties of the composite were studied. The use of the composite causes the growth of young tissue of the articular cartilage with the restoration of its structures.