Impact of surfactant on renal function of adult wistar rats

Abstract

The study is focused on elucidate the effect of Laprol-604 on rat renal function. The model of intoxication was produced by oral administration of water solution Laprol-604 to rats of experimental groups. The Laprol-604 administration induced electrolyte imbalance in blood serum and urine of rats. The obtained results testify the renal excretion of nitrogen metabolism products was decreased by the influence of Laprol-604. The adverse effect of Laprol-604 depended on its dose.