Albuminuria as an Independent Factor of Cardiovascular Complications in Patients with Comorbid Pathology

Abstract

The necessity of determining and assessing the dynamics of albuminuria and glomerular filtration rate in patients with type 1 and type 2 DM (as an early marker of endothelial dysfunction and a predictor of cardiovascular complications) was substantiated amid pathogenetic therapy with glycosaminoglycan sulodexide. There is a clinically significant decrease in the levels of both total protein and albumin in the urine, which along with an increase in glomerular filtration rate indicates an improvement in renal microcirculation. It is worth pointing out that the increase in glomerular filtration rate is mostly evident among type 2 DM patients with comorbid non-alcoholic fatty liver disease.