Functionаl fund of iron аnd solublе trаnsfеrrin rеcеptor аs а mаrkеr of еrythropoiеsis аctivity in pаtiеnts with аnеmiа on bаckground of chronic hеаrt fаilurе аnd chronic kidnеy disеаsе
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Date
2018
Authors
Єрмак, Олександра Сергіївна
Ebenezer, Aheto
Yermak, Oleksandra
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Abstract
Prevalence of anemia in patients with chronic heart failure (CHF) and chronic kidney
disease (CKD) rises up to 79%, depending on diagnostic definition, disease severity and patient
characteristics. Thus, anemia has been recognized as a very common and serious comorbidity in
patients with cardiorenal pathology. A clear association of anemia with worse prognosis has been
confirmed in multiple heart failure trials. Interest of researchers focused on the study of new markers
for assessing the functional state of red bone marrow in anemic patients with various underlying
pathological conditions.
The aim - to evaluate the functional fund of iron based on determining the dynamics of transferrin
saturation (TSAT) and activity of erythropoiesis based on determining the dynamics of soluble
transferrin receptor (sTfR) level in patients with CHF and CKD with anemia varying grades of
severity.
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Yermak O. Functionаl fund of iron аnd solublе trаnsfеrrin rеcеptor аs а mаrkеr of еrythropoiеsis аctivity in pаtiеnts with аnеmiа on bаckground of chronic hеаrt fаilurе аnd chronic kidnеy disеаsе / O. Yermak, A. Ebenezer // ISIC-2018 : [International Scientific Interdisciplinary Conference for medical students and young scientists, Kharkiv, 23–25 May, 2018] : abstract book / KNMU. – Kharkiv, 2018. – P. 141.