Neurocysticercosis with symptomatic epilepsy manifestation

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Date

2021-08

Authors

Nekrasova, Nataliya
Tovazhnyanska, Olena
Sushetska, Daryna
Markovska, Olena
Shapkin, Anton
Singh, Rhea
Soloviova, Yevhenija
Butov, Dmytro

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Abstract

To present a unique case of a 22-year-old male patient with symptomatic epilepsy manifestation on a background of neurocysticercosis (NCC). An Indian student in Kharkiv, who lived in rural parts in India, presented with sudden episodes of seizure followed by severe headaches. Laboratory analyses and neurological status (MRI) were performed. Neurological status of the patient revealed nystagmus and difficulty in performing co-ordination tests. General analysis of blood showed raised eosinophil count to 8%. The MRI showed a few small conglomerating peripherally enhancing thick-walled infective granulomas in left frontal lobe with extensive surrounding oedema in the left fronto-parietal lobe. The patient was treated with albendazol, levipil, methylprednisolone and pantoprazole. Clinical symptoms and subsequent MRI showed improvement. Neurocysticercosis is often misdiagnosed in the early stages, which leads to adverse outcomes. Although seizures are the most common clinical manifestation, it is a symptom that is not found in majority of the patients. The NCC of adult onset accompanying epileptic seizures is not well studied and a link between the helminthic invasion, epilepsy and psychiatric conditions needs to be established. This disease is potentially eradicable with wellplanned eradication programs targeting all stages of Taenia solium life cycle

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Keywords

granuloma, frontal lobe, seizures, Taenia solium

Citation

Neurocysticercosis with symptomatic epilepsy manifestation / N. Nekrasova, O. Tovazhnyanska, D. Sushetska, O. Markovska, A. Shapkin, Rhea Singh, Ye. Soloviova, D. Butov // Medicinski Glasnik. – 2021. – Vol. 18, № 2. – Р. 444–449.