Genetic markers of arterial hypertension prognosis in patients with diabetes mellitus type 2
Date
2018-04-18
Authors
Pasiyshvili, Tamara
Coryak, Veronika
Zhelezniakova, Natalia
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The European Society of Cardiology in its recommendations noted
that the development of arterial hypertension (AH) is due to the
presence of a large number of mutations in genes that monitor the
main blood pressure monitoring systems. That is, AH is considered
as a highly heterogeneous disease with a multifactorial etiology and
polygenic changes. The prevalence of the disease is so high (up to
30% of the world’s population), the complications that arise are so
serious and arterial pressure in most cases remains uncontrollable,
that the disease is considered to be socially significant, which affects
not only the quality of life, but also the mortality of patients. The
high prevalence among all causes of morbidity allows to assume its
combination with other diseases of internal organs, among which a
special place is occupied by diabetes mellitus (DM). The defeat of
the vascular system against the background of changes in all types
of metabolism leads to serious complications when combined.
Purpose: diagnostic optimization of the combined course of AH and
type 2 diabetes mellitus by establishing the role of the ACE and NOsynthase
genes polymorphism.
Description
Keywords
arterial hypertension, type 2 diabetes mellitus
Citation
Pasiyshvili Т. М. Genetic markers of arterial hypertension prognosis in patients with diabetes mellitus type 2 / T. M. Pasiyshvili, N. M. Zheleznyakova, V. V. Coryak // VI Евразийский конгресс кардиологов, Москва, 18–19 апреля 2018 г. : тезисы / Евразийская ассоциация кардиологов [и др.]. – Москва, 2018. – С. 5–6.