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Correlation between the lymphocyte-monocyte ratio and cytokines in chronic inflammation in rats treated with allogeneic mesenchymal stem cells

dc.contributor.authorPetryk, Nataliia
dc.contributor.authorShevchenko, Oleksandr
dc.date.accessioned2020-11-30T17:59:27Z
dc.date.available2020-11-30T17:59:27Z
dc.date.issued2020
dc.description.abstractThe inflammation model was chronic aseptic myositis caused by an intramuscular injection of 10mg λ-carrageenan (Sigma-Aldrich GmbH). Our experimental groups of rats were treated with MSCs (the injection into the inflamed site) in the amount of 1-2 million cells once. Blood sampling was performed from 6 hours to 28 days. We calculated our results using Statistica (data analysis software) version 13. For comparison, we used one-way ANOVA, Turkey's post hoc test, where p <0.05 was considered statistically significant. In our experiment, the correlation between levels of α-TNF, IL-6, and CRP with LMR in rats was described for the first time, demonstrating the suppression of chronic inflammation through MSCsen_US
dc.identifier.citationPetryk N. D. Correlation between the lymphocyte-monocyte ratio and cytokines in chronic inflammation in rats treated with allogeneic mesenchymal stem cells / N. D. Petryk, O. M. Shevchenko // Inter collegаs. – 2020. – Vol. 7, N 3. – Р. 109–111.en_US
dc.identifier.urihttps://repo.knmu.edu.ua/handle/123456789/27636
dc.language.isoenen_US
dc.subjectlymphocyte-monocyte rateen_US
dc.subjectC-reactive proteinen_US
dc.subjectchronic inflammationen_US
dc.subjectmesenchymal stem cellsen_US
dc.subjecttumor necrosis factor-αen_US
dc.subjectinterleukin-6en_US
dc.titleCorrelation between the lymphocyte-monocyte ratio and cytokines in chronic inflammation in rats treated with allogeneic mesenchymal stem cellsen_US
dc.title.alternativeКореляція між лимфоцитарно-моноцитарний співвідношенням і цитокінами при хронічному запаленні у щурів, які отримували алогенні мезенхімальні стовбурові клітиниen_US
dc.typeArticleen_US

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