The role of tumor necrosis factor-alfa in pathogenesis of nonalcoholic fatty liver disease
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Abstract
Tumor necrosis factor-α (TNF-α) is an adipokine that can cause the cytotoxic effects and can stimulate the apoptosis, impairing liver function. There is a need in further study of TNF-α influence on liver cells properties and its role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) against the background of diabetes mellitus (DM) type 2 and obesity.
Purpose. To assess the correlation between TNF-α and indexes of liver function in patients with NAFLD combined with DM type 2 and obesity.
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Romanenko V. The role of tumor necrosis factor-alfa in pathogenesis of nonalcoholic fatty liver disease / V. Romanenko, O. Ogneva // 8th Іnternational Scientific Іnderdisciplinary Сongrence for medical students and young scientists (ISIC), Kharkiv, 14th–15th of May 2015 : abstract book / KhNMU. – Kharkiv, 2014. – Р. 91.