A parallel liquid-phase synthesis of 5-(1H-4-pyrazolyl)-[1,2,4]oxadiazole libraries
| dc.contributor.author | Borisov, Aleksandr | |
| dc.contributor.author | Detistov, Oleksandr | |
| dc.contributor.author | Pukhovaya, Viktoriya | |
| dc.contributor.author | Zhuravel, Irina | |
| dc.contributor.author | Kovalenko, Sergei | |
| dc.date.accessioned | 2012-09-19T06:47:07Z | |
| dc.date.available | 2012-09-19T06:47:07Z | |
| dc.date.issued | 2009 | |
| dc.description.abstract | Combinatorial libraries of substituted 3-(methylthio)-5-(amino)-4-([1,2,4]oxadiazol-5-yl)-1H-pyrazoles 6,10, 13, 15 (395 members, yields 32-87%), 4-([1,2,4]oxadiazol-5-yl)-1H-3,5-pyrazolediamines 8, 11 (571 members, yields 25-83%), 2-(methylthio)-3-([1,2,4]oxadiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-ones 17(85 members, yields 56-95%), and 2-(amino)-3-([1,2,4]oxadiazol-5-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-ones 18 (110 members, yields 56-95%) were synthesized by the parallel liquid-phase synthesis method. | uk_UK |
| dc.identifier.citation | A parallel liquid-phase synthesis of 5-(1H-4-pyrazolyl)-[1,2,4]oxadiazole libraries / A. V. Borisov, O. S. Detistov, V. I. Pukhovaya, I. O. Zhuravel, S. M. Kovalenko // J. Comb. Chem. – 2009. – Vol. 11. – P. 1023–1029. | uk_UK |
| dc.identifier.issn | 1520-4766 | |
| dc.identifier.uri | https://repo.knmu.edu.ua/handle/123456789/817 | |
| dc.language.iso | en | uk_UK |
| dc.publisher | American Chemical Society | uk_UK |
| dc.subject | [1,2,4]oxadiazoles | uk_UK |
| dc.subject | medicinal chemistry | uk_UK |
| dc.subject | parallel liquid-phase synthesis | uk_UK |
| dc.subject | pyrazoles | uk_UK |
| dc.subject | combinatorial libraries | uk_UK |
| dc.title | A parallel liquid-phase synthesis of 5-(1H-4-pyrazolyl)-[1,2,4]oxadiazole libraries | uk_UK |
| dc.type | Article | uk_UK |