Urogenital inflammatory diseases in women of reproductive age as a cause of an unhealthy start of children`s life: Ukrainian and European research

Abstract

Maternal and child health is the most important medical and social problem in the world. Modern scientific research of the world leading specialists has shown that fetus and newborn adaptive reserves depend to a greater extent on case of maternal diseases during pregnancy, especially infectious diseases, which can definitely lead to pathology of various organs and systems in fetus, defects in immune response, metabolic problems and affect life expectancy. Maternal infectious-inflammatory process in genitourinary system can act as one of the factors that damages embryogenesis of kidneys at organ, tissue and subcellular levels. Studies have shown an increase in case number of kidneys and urinary tract congenital abnormalities among children exposed to such mathernal pathology in utero. The results of Ukranian and European research indicate that chronic inflammatory diseases of mother genitourinary system are a damaging factor that leads to development of kidney pathology in children at various stages of ontogenesis. In order to prevent the development of nephropathology in children, it is absolutely necessary to carry out, firstly, measures directed to prevent the development of urogenital inflammatory diseases in women of reproductive age, and secondly, in-time detection and treatment of the specified pathology in this category of persons. Thus, the presence of chronic inflammatory diseases of the genitourinary system i pregnant woman is an unfavourable background in course of pregnancy, on which the possibilities of adaptative mechanisms are reduced or limited, various complications of pregnancy arise and fetus kidneys morpho-functional state changes. And this in future will lead to development of various kidney pathologies.