Please use this identifier to cite or link to this item:
http://repo.knmu.edu.ua/handle/123456789/31430
Title: | Morphological peculiarities of cerebral injury in polyomavirus infection in HIV-positive individuals |
Authors: | Zhelezniakova, Natalia Bondarenko, A. Katsapov, D. Pasiieshvili, Tamara Bocharova, Tetiana Gargin, Vitaliy |
Keywords: | JC-virus BK-virus polyomavirus infection Human immunodeficiency virus (HIV) |
Issue Date: | 2022 |
Citation: | Morphological peculiarities of cerebral injury in polyomavirus infection in HIV-positive individuals / N. M. Zhelezniakova, A. V. Bondarenko, D. V. Katsapov, T. M. Pasiieshvili, T. V. Bocharova, V. V. Gargin // Аzerbaijan Medical Journal. – 2022. – № 3. – P. 101–107. |
Abstract: | The article presents information about the study of morphological features in progressive multifocal leukoencephalopathy caused by polyomavirus infection in HIV-infected individuals. A study of sectional material (the brain) was carried out. After routine proceeding and histological staining, the slides were studied under Olympus BX41 microscope, followed by a morphometric examination. According to neuroimaging methods, the presence of multiple foci in the brain may be caused by the presence of several etiological factors: JCV, BKV, EBV, T. gondii, and C. neoformans, which requires mandatory laboratory confirmation. Morphological changes in the brain in PML caused by JCV and BKV are characterized by areas of demyelinated lesions 2-3 mm in size with a tendency to merge, with significant areas of white matter affected and degenerative changes predominantly in the juxtacortical/subcortical white matter. |
URI: | http://repo.knmu.edu.ua/handle/123456789/31430 |
Appears in Collections: | Наукові праці. Кафедра внутрішньої медицини № 1 |
Files in This Item:
File | Description | Size | Format | |
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Zhelezniakova_Аzerbaijan Medical Journal.pdf | 517,51 kB | Adobe PDF | View/Open |
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