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http://repo.knmu.edu.ua/handle/123456789/31046
Title: | Creation of anti-inflammatory pharmaceutical compositions (review) |
Authors: | Syrova, Ganna Petyunina, Valentina Makarov, Volodimir Lukіаnova, Larysa Chalenko, Natalia |
Keywords: | pain inflammation caffeine non-narcotic analgesics nonsteroidal anti-inflammatory drugs pharmaceutical composition |
Issue Date: | 13-Nov-2022 |
Citation: | Creation of anti-inflammatory pharmaceutical compositions (review) / G. O. Syrova, V. M. Petyunina, V. O. Makarov, L. V. Lukianova, N. M. Chalenko // Inter Collegas. – 2022. – Vol. 9, No 1. – P. 93 –101. |
Series/Report no.: | doi: 10.35339/ic.9.1.93-101 |
Abstract: | The review article summarizes the data of literature and our own research on the creation of more effective and safe domestic combined drugs with a pronounced anti-inflammatory and analgesic effect. Untimely treatment of inflammatory processes often leads to long-term incapacity and even disability, so today there is an active search for new effective and safe domestic combination drugs with pronounced anti-inflammatory and analgesic effects. Due to the constant search for innovative drugs the treatment of a significant number of diseases and pathological conditions with existing drugs remains ineffective or causes addiction and a large number of side effects. As a result, inflammatory processes can be accompanied by severe pain, spasms, increased convulsive activity of the brain, other disorders, so non-narcotic analgesics and nonsteroidal anti-inflammatory drugs are combined with other agents that can cause complementary effects or potentiate each other's effects. Caffeine is a useful adjuvant of nonsteroidal anti-inflammatory drugs of various chemical structures in terms of anti-inflammatory and analgesic effects. The article presents a literature review of the current state of treatment of inflammation and pain, conducting research to expand the therapeutic capabilities of known pharmaceuticals, the creation of pharmaceutical compositions of nonsteroidal anti-inflammatory drugs with caffeine. |
URI: | http://repo.knmu.edu.ua/handle/123456789/31046 |
Appears in Collections: | Наукові праці. Кафедра медичної та біоорганічної хімії |
Files in This Item:
File | Description | Size | Format | |
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IC 9(1)2022.pdf | 1,01 MB | Adobe PDF | View/Open |
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