Please use this identifier to cite or link to this item:
http://repo.knmu.edu.ua/handle/123456789/28532
Title: | Tourette syndrome or PANDAS—a case report |
Authors: | Singh, Rhoa Nekrasova, Natalya Butov, Dmytro |
Keywords: | new-onset tics anti-neuronal antibodies obsessive-compulsive disorder streptococcal infections adolescent female |
Issue Date: | 21-Sep-2020 |
Citation: | Singh R. Tourette syndrome or PANDAS—a case report / R. Singh, N. Nekrasova, D. Butov // Wiener Medizinische Wochenschrift. – 2020. – DOI: https://doi.org/10.1007/s10354-020-00779-6. |
Abstract: | Tourette syndrome (TS), a relatively common disorder, has been gaining more attention during the past two decades because of an increased number of reports. Nevertheless, it is still not completely understood. Furthermore, a clinical entity called “pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections” (PANDAS) has been introduced, which describes a tic disorder, accompanied by psychiatric disorders such as obsessive compulsive disorder (OCD), after a streptococcal infection in childhood. We present a case report of a 19-year-old adolescent Ukrainian female, with a history of anxiety disorder and OCD, who, despite TS remission during childhood, presented with new-onsetmotor and phonic tics after 1 month of severe tonsillitis. Blood and cerebrospinal cultures showed Streptococcus pyogenes, with magnetic resonance imaging revealing hypo-intense changes in the caudate nucleus on both sides. Treatment with clonazepam and fluoxetine, along with behavioral therapy, have improved the severity of her condition. This report presents a case of TS reemergence against the background of immunological reaction or PANDAS with a late adolescent onset. |
URI: | https://repo.knmu.edu.ua/handle/123456789/28532 |
Appears in Collections: | Наукові праці. Кафедра неврології № 2 |
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Tourette syndrome or PANDAS—a case report.pdf | 237,87 kB | Adobe PDF | View/Open |
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