Indicators of protective cytokin and fibrator factor in patients with chronic heart failure with a different functional class on ischemic heart disease and composition 2 type diabetes mellitus
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In patients with CHF in CHD with concomitant type 2 diabetes, high activity of IL-1β and MCP-1 is detected in comparison with patients without diabetes. In patients with CHF in coronary heart disease with type 2 diabetes and without it, there is an increase in the prophylactic parameter of MCP-1 and proinflammatory cytokine IL-1β in parallel with the growth of FC CHF. The presence of type 2 diabetes negatively affects the work of cytokines and markers of fibrosis, which is confirmed by higher levels of IL-1β and MCP-1 in comparison with patients without type 2 diabetes in the presence of the same FC of CHF.
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Narizhna A. V. Indicators of protective cytokin and fibrator factor in patients with chronic heart failure with a different functional class on ischemic heart disease and composition 2 type diabetes mellitus / A. V. Narizhna, D. V. Olkhovsky // Український кардіологічний журнал. – 2019. – Том 26, додаток 1 : ХХ Національний конгрес кардіологів України, Київ, 25–27 вересня 2019 р. : матеріали конгресу. – С. 90–91.