Clinical and immunological indices in hiv-infected patients with viral skin diseases

Abstract

The purpose of the present research was to study a number of immunological indices in HIV/AIDS-infected patients with viral skin lesions. Our follow-up involved 38 cases with skin pathology against a background of HIV/AIDS infection at the age of 18-53 years (20 men and 18 women). The patients had viral pathology (20 cases with recurrent herpes simplex and 18 ones with chronic ulcerative herpes simplex). There were 25 patients with HIV infection stage 2, and 13 with stage 3. Immunological studies were carried out before the treatment and 2 months after it. Together with ART, the treatment in cases of chronic ulcerative herpes and recurrent herpes simplex included acyclovir, 400 mg 5 times a day, and Cidipol solution externally. Group 1 received ART according to the protocol and antiviral therapy. Group 2 received ART, antiviral medicines and Cidipol solution externally. Studies of the above relationships in cases of viral lesions in HIV/AIDS-infected patients will make it possible to fully understand the cytokine response, thereby enabling us to increase the efficacy of the given therapy and prevention of viral dermatoses in such patients.