Development of specification for substance 7-azepan-1- il-1-ethil-6-ftor-3- (4-phenyl-1, 3-tiazol-2-il) - Quinoline- 4 (1h)-one
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Abstract
The paper presents the results of the development of specifications for a new first-synthesized chemical
compound exhibiting antibacterial activity and positioned as a perspective drug substance. According to
the recommendations of the European Pharmacopoeia quality control procedures have been developed
for standardization the substance of 7-azepan-1-yl-1-ethyl-6-fluoro-3-(4-phenyl-1,3-thiazol-2-yl))-
quinoline-4(1H)-one - a modified derivative of the fluoroquinolone series.
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Development of specification for substance 7-azepan-1- il-1-ethil-6-ftor-3- (4-phenyl-1, 3-tiazol-2-il) - Quinoline- 4 (1h)-one / N. V. Spyrydonova, A. V. Silin, V. A. Lebedynets, O. A. Zavada, O. S. Kalinenko // The Pharma Innovation Journal. – 2019. – V. 8 (5). – P. 54–56.