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http://repo.knmu.edu.ua/handle/123456789/22757
Title: | Development of specification for substance 7-azepan-1- il-1-ethil-6-ftor-3- (4-phenyl-1, 3-tiazol-2-il) - Quinoline- 4 (1h)-one |
Authors: | Spyrydonova, N. Silin, A. Lebedynets, Vyacheslav Zavada, O. Kalinenko, Olga |
Keywords: | quality control method specification active pharmaceutical ingredient quinolone antibacterial agent |
Issue Date: | May-2019 |
Citation: | Development of specification for substance 7-azepan-1- il-1-ethil-6-ftor-3- (4-phenyl-1, 3-tiazol-2-il) - Quinoline- 4 (1h)-one / N. V. Spyrydonova, A. V. Silin, V. A. Lebedynets, O. A. Zavada, O. S. Kalinenko // The Pharma Innovation Journal. – 2019. – V. 8 (5). – P. 54–56. |
Abstract: | The paper presents the results of the development of specifications for a new first-synthesized chemical compound exhibiting antibacterial activity and positioned as a perspective drug substance. According to the recommendations of the European Pharmacopoeia quality control procedures have been developed for standardization the substance of 7-azepan-1-yl-1-ethyl-6-fluoro-3-(4-phenyl-1,3-thiazol-2-yl))- quinoline-4(1H)-one - a modified derivative of the fluoroquinolone series. |
URI: | https://repo.knmu.edu.ua/handle/123456789/22757 |
Appears in Collections: | Наукові праці. Кафедра медичної та біоорганічної хімії |
Files in This Item:
File | Description | Size | Format | |
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Development of specification for substance.pdf | 541,88 kB | Adobe PDF | View/Open |
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