Кафедра пропедевтики педіатрії
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Item The influence of consuming vitamin medications on children(2024) Вакуленко, Аліна Іванівна; Ащеулов, Олександр Михайлович; Vakulenko, A.; Ashcheulov, O.Item Особливості фізичного розвитку дітей різного віку : методичні вказівки для здобувачів вищої освіти 3-го курсу (спеціальність «Медицина»)(ХНМУ, 2024) Фролова, Тетяна Володимирівна; Стенкова, Наталія Федорівна; Терещенкова, Ірина Іванівна; Сіняєва, Ірина Ревазівна; Осман, Наталія Сергіївна; Frolova, Tetyana; Stenkova, Natalia; Tereshchenkova, Iryna; Siniaieva, Iryna; Osman, NataliaItem Comorbidity and impact of bronchial asthma to gastroesophageal reflux disease in children(2024) Карпушенко, Юлія Валентинівна; Кarpushenko, Yuliia; Фролова, Тетяна Володимирівна; Frolova, Tetyana; Дробова, Надія Миколаївна; Drobova, Nadiia; Ащеулов, Олександр Михайлович; Ashcheulov, OleksandrGastroesophageal reflux disease (GERD) is a highly comorbid disease with bronchial asthma (BA). The relationship between GERD and BA is complicated and controversial. Aim: to analyze impact factors of BA and GERD in children with comorbid pathology for the further development of early diagnostic and preventive measures. Materials and methods. 81 children (aged 6 to 18 years) were involved in the study and divided into two groups: children with GERD and BA as a main group (n=27) and children with GERD and without allergy as a control group (n=54). The verification of diagnoses was carried out according to the unified clinical protocols of medical care. The results were processed using nonparametric statistical methods. Results. Esophageal motility disorders (EM) were detected in 100% of patients with BA, regardless of the severity. Inflammatory changes of the esophageal mucosa (EM) were equally frequently detected in patients with mild and moderate persistent BA, and were absent in patients with severe BA. GERD was diagnosed in 44.4% of patients with BA. 25.0% of patients had the erosive form of GERD, 25.0% — non-erosive GERD, 50.0% — endoscopically negative GERD, in the control group — 33.0%, 35.0%, 32.0% respectively. Conclusion. All patients with BA had esophageal motility disorders. GERD was diagnosed in 44.4%. Inflammatory changes of EM (erosive and non-erosive forms of GERD) were detected in 22.0% of patients with mild and moderate forms of BA, and in severe forms of BA — endoscopically negative GERD. The frequency of inflammatory changes reached 68.0% in the control group. The research was carried out in accordance with the principles of the Declaration of Helsinki. The study protocol was approved by the Local Ethics Committee of the institution indicated in the work. The informed consent of children's parents was obtained for conducting the studies. No conflict of interests was declared by the authors.Item Clinical report of Mediterranean fever in a child in Ukraine – Don’t miss it!(2024) Pashenko, К.Y.; Фролова, Тетяна Володимирівна; Frolova, Tetyana; Карпушенко Юлія Валентинівна; Кarpushenko, Yuliia; Muratov, G.R.; Savvo, О.М.; Khalturina, Т.О.; Ащеулов, Олександр Михайлович; Ashcheulov, OleksandrIntroduction. Familial Mediterranean fever (FMF) is a non-infectious genetic disease caused by a mutation in the MEFV gene. This disease is more common in people of Mediterranean or Middle Eastern descent, but can occur in any ethnic group, including those living European countries. FMF has typical clinical symptoms. Its long term without appropriate treatment the disease can lead to a violation of the child's physical development and result in the development of amyloidosis. The aim is to focus the attention of the medical community of Ukraine and inform European medical specialists on the FMF cases due to migration changes in Ukraine. This article presents a clinical case of FMF in a 4-year-old child who was admitted to our hospital with complaints of fever, abdominal pain, vomiting, and stool retention. Additional examination included: laboratory tests (complete blood count, urinalysis, biochemical blood test with determination of liver and kidney tests); instrumental methods: ultrasound examination of the abdominal organs and urinary system, X-ray examination of the abdominal organs with contrast. The results of additional tests revealed the signs of inflammatory process and impaired kidney function. When clarifying the family medical history, it was revealed that the older brother suffers from FMF (a mutation of the MEFV genotype was determined) and takes specific therapy (colchicine). The final diagnosis was determined: Acute strangulated intestinal obstruction Familial Mediterranean Fever (clinically). Peritonitis. Operative laparoscopic and conservative treatment was performed. The patient was discharged in a satisfactory condition with appropriate recommendations. Conclusions. The number of FMF cases in children have increased due to changes in the migration process in Ukraine. The relevance of this disease has increased. Taking into consideration a significant migration of population, the likelihood of an increase in the number of cases of FMF in European countries is increasing, which requires awareness among a wide range of doctors. In this report we have described a pediatric FMF case which was represented by recurrent episodes of fever, abdominal pain, impaired kidney function test results, and inflammatory markers. A determined mutation of the MEFV genotype in the brother of our patient makes the diagnosis of FMF unquestionable. The research was carried out in accordance with the principles of the Helsinki Declaration. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the authors.Item Новонароджена дитина. Особливості методики обстеження та догляду(2024-02-29) Фролова, Тетяна Володимирівна; Стенкова, Наталія Федорівна; Терещенкова, Ірина Іванівна; Серветник, Анжела Володимирівна; Дробова, Надія МиколаївнаItem Догляд за дітьми, його роль у лікувальному процесі та організація роботи в умовах педіатричного стаціонару(2024-02-29) Фролова, Тетяна Володимирівна; Сіняєва, Ірина Ревазівна; Осман, Наталія Сергіївна; Амаш, Анастасія Григорівна; Дробова, Надія Миколаївна; Серветник, Анжела Володимирівна; Кожина, Ольга СергіївнаItem Симуляція практичних навичок щодо догляду за дітьми в умовах педіатричного стаціонару(2024-04-25) Фролова, Тетяна Володимирівна; Терещенкова, Ірина Іванівна; Карпушенко, Юлія Валентинівна; Ащеулов, Олександр Михайлович; Сенаторова, Анастасія Валеріївна; Осман, Наталія СергіївнаItem Вплив дистанційного навчання на школярів(2024) Ращупкіна, Зінаїда Едуардівна; Ащеулов, Олександр МихайловичItem Значення скринінгу новонародженого(2024) Вакуленко, Аліна Іванівна; Ащеулов, Олександр МихайловичItem Cон дитини в умовах війни: психологічні виклики(2024) Пашкова, Анастасія Євгенівна; Нечитайло, Софія Сергіївна; Ащеулов, Олександр Михайлович