Dental supportive care in breast cancer patients during adjuvant chemotherapy

Abstract

The oral cavity toxicity is observed in 84.6-96.2% of patients, and increases with the number of cycles of chemotherapy. The main manifestations of the side-effects of cytostatic therapy are cheilitis and mucositis. Application of complex of therapeutic and preventive measurements, developed by us, as a support therapy in this patients, has contributed to a significant reduction o dental toxicity, compared to the control group in 1.5 times on the I cycle (56.9%), and in 4.5 times on the VI cycle of CTx (18,1%). This demonstrates the effectiveness of the applied complex of therapeutic and preventive measurements in breast cancer patients during adjuvant chemotherapy. The above-mentioned data dictates the necessity of monitoring of the oral cavity status in breast cancer patients during the treatment.