Wound healing effect thiotriazoline ointment for action on skin ionizing radiation in rats
| dc.contributor.author | Zvyagintseva, T. | |
| dc.contributor.author | Mironchenko, Svetlana | |
| dc.contributor.author | Ganziy, Tetyana | |
| dc.contributor.author | Zhelnin, E. | |
| dc.date.accessioned | 2014-11-12T11:06:43Z | |
| dc.date.available | 2014-11-12T11:06:43Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | We studied the healing and immunomodulatory effects of "Unguentum Thiotriazolini 2%" ("Chemical-pharmaceutical plant "Krasnaya zvezda", Ukraine) in rats with local radiation skin damage. There were 4 groups of rats, each comprised of 6 animals: intact (group 1), skin damage (group 2), skin damage + ointment: methyluracil (group 3) and thiotriazoline (group 4). Rats of 2, 3 and 4 groups were exposed to X-rays of the hip (80 Gy). In groups 3 and 4 the ointments were applied on the skin 1 hour before exposure and for 10 days after it once a day. On 35th day of the experiment immunomorphological study area of exposure (macrophages, cells-producers of interleukins IL-1 and IL-10) was performed. The results showed that the thiotriazoline ointment (group 4) caused more pronounced wound healing effect, manifested by increased macrophage reaction, restoration of cytokine balance, compared with groups 2 and 3. | uk_UA |
| dc.identifier.citation | Wound healing effect thiotriazoline ointment for action on skin ionizing radiation in rats / T. V. Zvyagintseva, S. I. Mironchenko, T. V. Ganziy, E. V. Zhelnin // Inter collegas. – 2014. – Vol. 1 (1). – P. 25–30. | uk_UA |
| dc.identifier.uri | https://repo.knmu.edu.ua/handle/123456789/7482 | |
| dc.language.iso | en | uk_UA |
| dc.subject | Thiotriazoline ointment | uk_UA |
| dc.subject | wound healing effect | uk_UA |
| dc.subject | ionizing irradiation of the skin | uk_UA |
| dc.title | Wound healing effect thiotriazoline ointment for action on skin ionizing radiation in rats | uk_UA |
| dc.type | Article | uk_UA |