Malignant tumors of the appendix: clinical and morphological analysis of cases from the practice
Date
2021-05
Authors
Myroshnychenko, Mykhailo
Dyadyk, Olena
Kapustnyk, Nataliia
Fedulenkova, Yuliia
Borzenkova, Iryna
Astapieva, Olha
Selivanova, Larisa
Zakharenko, Valentyna
Lytvynenko, Olena
Molodan, Dmytro
Journal Title
Journal ISSN
Volume Title
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Abstract
The authors have analyzed medical histories of two patients, treated in health care facilities of Kharkiv region from 2008 to 2020. These patients underwent urgent appendectomy, given the existing clinic of acute appendicitis. Morphological examination of the surgical material allowed us to diagnose adenocarcinoma in one case, and neuroendocrine tumor in combination with endometriosis in the other case. Morphological examination of the surgical material in the first case revealed a moderately differentiated adenocarcinoma and diffuse neutrophilic infiltration in all layers of the appendix, and in the second case – a well-differentiated neuroendocrine tumor (G3), combined with the signs of phlegmonous-ulcerative appendicitis and loci of endometriosis. In both cases, there were no specific for the oncological process anamnestic and clinical-instrumental data, and these tumors were manifested by the clinic of acute appendicitis. Only morphological examination of the surgical material allowed identifying the pathological process. Clinical and morphological analysis of cases from the practice of malignant tumors of the appendix (neuroendocrine tumor and adenocarcinoma) will be useful and interesting for the medical community and should stimulate cancer vigilance in physicians.
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Keywords
adenocarcinoma, clinical and morphological analysis, neuroendocrine tumor, appendix
Citation
Malignant tumors of the appendix: clinical and morphological analysis of cases from the practice / M. S. Myroshnychenko, O. O. Dyaduk, N. V. Kapustnyk, Y. Ya. Fedulenkova, I. V. Borzenkova, O. M. Astapieva, L. I. Selivanova, V. V. Zakharenko, O. Yu. Lytvynenko, D. V. Molodan, O. I. Paskevych, K. Od. Akritova, B. I. Melnik, V. M. Bobrova // Wiadomosci Lekarskie. – 2021. – Volume LXXIV, issue 5. – Р. 1277–1280.