Lipid peroxidation and antioxidant activity in oral fluid of patients with chronic generalized periodontitis: еffect of periodontal treatment

Abstract

The research demonstrates pathogenetic role of abnormal processes of lipid peroxidation and antioxidant defense in the oral fluid in their connection with clinical change in development of CGP of initial-I degrees of severity. The scheme of complex treatment of periodontitis by means of local application of lipoflavon using individual periodontal polyvinylchloride delivery tray contributing to inflammation elimination and long-term remission has been developed. High therapeutic efficiency of the LQLC was shown to be determined by antioxidant, membranotropic, antiinflammatory effects. This allows to recommend lipoflavon for local application as pathogenetically substantiated drug in treatment of generalized periodontitis.