The influence of phosphorus complex organic mixtures on the content of sexual hormones and gonadotropins in the serum with violations in the reproductive system

Simple item page
dc.contributor.authorZharova, A.
dc.contributor.authorBagmut, I.
dc.contributor.authorTitkova, A.
dc.contributor.authorMarakushyn, Dmytro
dc.contributor.authorRezunenko, Yu.
dc.date.accessioned2017-12-06T08:32:49Z
dc.date.available2017-12-06T08:32:49Z
dc.date.issued2017-12
dc.descriptionThus, complex organic phosphorus compounds - Efasol, Polifos-72, Syntaf 10- 18 at doses of 1/10 and 1/100 LD50 at long subtoxical action can inhibit the synthesis and secretion of gonadotropins (FSH, LH, PL) and hormones (ED, PG). Under such circumstances the genital dysfunction, disorders of the formation of secondary sexual characteristics, violation of ovarian-menstrual cycle and lactation should be expected. The Journal of Medicine and Philosophy 1311 Thus, in terms of working environment and a significant burden on the body of phosphorus compounds the formation of dysfunction in sexual instinct and mental status in women may be expected. The analysis shows that a significant inhibition of gonadotropin secretion may be combined with the permeability of the haemato-encephalic barrier for phosphorus complex organic compounds and their direct impact on the hypothalamic-pituitary neuroendocrine complexru_RU
dc.description.abstractAt 100 Wistar rat population in subacute experiment the effect of small doses of subtoxical phosphorus detergents (Efasol, Polifos, Syntaf) on the level of sex hormones in the blood serum of females - estrogen and gonadotropins was investigated by radioimmunoassay. There were 9 research groups and one control, 10 animals in each (N=100). Estrogen and gonadotropins were studied in rat serum. Significant inhibition of gonadotropin secretion may be combined with the permeability of the haemato-encefalic barrier for phosphorus complex organic compounds and their direct influence on the hypothalamic-pituitary neuroendocrine complex.ru_RU
dc.identifier.citationThe influence of phosphorus complex organic mixtures on the content of sexual hormones and gonadotropins in the serum with violations in the reproductive system / A. I. Zharova, I. Yu. Bagmut, A. V. Titkova, D. I. Marakushyn, Yu. K. Rezunenko // The Journal of Medicine and Philosophy. – 2017. – Issue 6 (2), (December), volume 42. – P. 1306–1310.ru_RU
dc.identifier.urihttps://repo.knmu.edu.ua/handle/123456789/18528
dc.language.isoenru_RU
dc.subjectxenobioticsru_RU
dc.subjectprogesteroneru_RU
dc.subjectprolactinru_RU
dc.subjectluteotropinru_RU
dc.subjectfollicle-stimulating hormoneru_RU
dc.subjectratsru_RU
dc.titleThe influence of phosphorus complex organic mixtures on the content of sexual hormones and gonadotropins in the serum with violations in the reproductive systemru_RU
dc.typeArticleru_RU

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
The Journal of Medicine and Philosophy (1)-repos.2017.pdf
Size:
750.23 KB
Format:
Adobe Portable Document Format
Download

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
11.51 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Наукові праці. Кафедра фізіології