Polycyclic systems containing 1,2,4-oxadiazole ring 2. 4-(1,2,4-oxadiazol-5-yl)pirrolidin-2-ones: synthesis and prediction of biological activity
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Date
2008
Authors
Kharchenko, Juliya
Detistov, Oleksandr
Orlov, V.
Journal Title
Journal ISSN
Volume Title
Publisher
Springer
Abstract
A one-pot synthesis of 5-oxopyrrolidine-3-carboxylic acids, carbonyldiimidazole, and benzamidoximes leads to the formation of the novel 4-(1,2,4-oxadiazol-5-yl)pyrrolidin-2-one bicyclic systems, the structures of which have been confirmed by IR and 1H NMR methods and by liquid chromato-mass spectrometry.
Description
Keywords
1,2,4-oxadiazole, pyrrolidin-2-ones, bicyclic systems, sinthesis
Citation
Kharchenko Yu. V. Polycyclic systems containing 1,2,4-oxadiazole ring 2. 4-(1,2,4-oxadiazol-5-yl)pirrolidin-2-ones: synthesis and prediction of biological activity / Yu. V. Kharchenko, O.S. Detistov, V.D. Orlov // Chemistry of Heterocyclic Compounds. – 2008. – Vol. 44. – P. 600–605.