Risk of injury hepatobiliary system in patients with subclinical and clinical hypothyroidism in conjunction with the autoimmune destruction thyroid glands.

Abstract

Conclusions. 1. Autoimmune thyroiditis is often accompanied by the hepatomegaly (in 76.8 % of cases) as a manifestation of the toxic effects of thyroid stimulating hormone in the liver’s parenchyma. 2. In patients with hypothyroidism, which is complicated for autoimmune thyroiditis, there was a significant increase in the level of cholesterol and β- lipoproteins in the blood serum, compared with patients with preserved function of the thyroid gland. 3. In patients with autoimmune thyroiditis and primary hypothyroidism in 76.8 % of cases, an increase in the content of transferases background hepatomegaly, which may be considered as its part in the pathological process with the development of reactive hepatitis. 4. The presence of reactive hepatitis and dyslipidemia in patients with autoimmune thyroiditis causes the feasibility of additional destination of statins and hepatoprotectors plant origin.