Research in regeneration of the prothetic bed mucous membrane of patients with metal dental orthopedic constractions

Abstract

The regeneration of the oral mucosal epithelium of patients with metal construction has some features: high proliferative activity of the basal and parabasal layers of the multilayer flat epithelium in the areas of acanthosis and almost double reduction of MI value in the areas of papillomatosis; high AI value of the basal layers of the multilayer flat epithelium in the areas of acanthosis, lack of expression of bcl-2 in epithelial cells of the entire thickness of the mucosa. Based on the histologic and immunohistochemistry data we can conclude, that the disturbance of the balance between cell proliferation and apoptosis may affect the efficiency of regenerative processes in the cases of damage, which is consistent with the opinion of other authors