Successful application of magnetite nanoparticles in the comprehensive therapy of multiple sclerosis: a clinical case

Abstract

Multiple sclerosis (MS) is a serious neurological disorder due to its widespread preva-lence, chronic nature, frequent progression to disability, and tendency to affect young people. The pathogenesis of MS is based on the immunopathogenesis hypothesis. Biocompatible magnetite nanoparticles, which exhibit selective sorption activity towards cell membrane surface proteins, circu-lating immune complexes, lymphocytotoxic antibodies, and the complement system, as well as en-hance phagocytic activity and the completion index of leukocyte phagocytosis, can be effectively used for immunocorrection. The main goal of the study is to slow the progression of MS, improve the neurological status and overall condition of the patient, and reduce the dynamics of the spread of demyelinating lesions in the brain.