Age-related changes of nesfatin-1 action in hypertensive women

Abstract

Arterial hypertension is the most common cardiovascular risk factor, which is often accompanied by metabolic disorders, such as obesity and/or dysglycemia. Nesfatin-1 was found as an anorexigenic peptide secreted in hypothalamus, adipose tissue, pancreas, reproductive organs etc. It was shown that nesfatin-1 is associated with the occurrence of hypertension, insulin production and sensitivity, hormonal status, in particular the level of sex hormones.