Dyslipidemia and waist to height ratio in hypertensive patients from Ukraine

Abstract

Overweight and obesity are common pathological conditions in the adult population of Ukraine and are associated with other chronic diseases, including hypertension, diabetes and dyslipidemia. All these diseases are key factors modified risk for other diseases, such as cardiovascular and renal disease. Early detection of these conditions will help in controlling their strategy. The aim of our study was to investigate the association of waist to height ratio (WHtR) in conjunction with the parameters of lipid metabolism in hypertensive patients. Methods. 73 hypertensive patients were examined. All patients underwent complex clinical examination which included estimation of complaints, history taking, physical and additional methods of examination. Following anthropometric parameters (WHtR) and parameters of lipid metabolism were measured. Data is represented as Me (Q25-Q75). Kruskal-Wallis and median test were used, р <0,05. Results. The hypertensive patients are characterized by increased levels of total cholesterol 5,67 (4,96- 7,11) mmol/L, triglyceride 2,75 (2,56-3,01) mmol/L, low-density lipoprotein-cholesterol 0,98 (0,83-1,35) mmol/L and decreased levels of highdensity lipoprotein-cholesterol 3,51 (2,77-4,54) mmol/L. Obesity was observed in 86% of hypertensive patients as measured by WHtR ≥0,5, dyslipidemia was detected in 73% patients as measured by levels of total cholesterol. In correlation analysis positive relations between WHtR and levels of total cholesterol (R=0,42; р<0,05) in hypertensive patients were found. Conclusions. The hypertension is accompanied by dyslipidemia, characterized by increased levels of total cholesterol, triglyceride, low-density lipoprotein-cholesterol and decreased levels of highdensity lipoprotein-cholesterol. Significant positive relationships between WHtR and levels of total cholesterol in hypertensive patients were detected, which is another confirmation of the clinical significance of this measurement and substantiates the need for screening patients with WHtR in determining obesity, dyslipidemia and cardiovascular risk.