Theoretical justification of the search for potential medicinal products containing food plant biologically active substances

Abstract

Considering that food plants have a stable raw material base and the proven safety to the human body the use of the raw material of food plants to create new medicines is relevant and has several advantages, such as a sufficient raw material base, significant efficiency and high safety level. Aim. To substantiate theoretically the search for potential medicinal products based on the food plant raw material, in particular carrot roots and parsnip roots. Materials and methods. Clinical and pharmacological analysis was conducted using the databases of scientific information (articles, monographs, abstracts of theses, etc.) from Ukraine and worldwide (NCBI, Vernadsky National Library of Ukraine, Google Scholar, Google Academy). This information contains data on the search, development, preclinical studies, clinical trials, application of medicinal products on the basis of the plant raw material, in particular carrot roots and parsnip roots, in officinal and folk medicine. Results. The study conducted has allowed us to prove the relevance, timeliness, expediency and prospect for searching new promising medicinal products on the basis of the raw material of food plants of the Apium genus – carrot and parsnip roots. Conclusions. The study has proven that the plants of the Apium genus – carrot and parsnip roots having a powerful, affordable and cheap raw material base are the sources of substances containing the amount of biologically active substances that are promising for the creation of new medicinal products on their basis with the cytoprotective, antiinflammatory, nephroprotective, wound healing, reparative action, and they are promising for introduction into medical practice for the treatment of skin lesions.