Undifferentiated connective tissue dysplasia syndrome in pregnant women as a cause of obstetric and perinatal pathology

Abstract

Undifferentiated connective tissue dysplasia syndrome (UCTDS) is the most common extragenital pathology of pregnant women in the musculoskeletal system. Connective tissue is widely represented in all human organs and systems including the reproductive system. Therefore, a change in the normal course of pregnancy and childbirth in women with the UCTDS is an expected pathological phenomenon. In general, the syndrome of UCTDS is typical for women, both pregnant and nonpregnant. Estrogens stimulate an increase in the number of mast cells, promotes edema of connective tissue and the formation of exudative reactions. Pregnancy changes the hormonal background and "aggravates" the course of the syndrome of UCTDS.