Markers of immune inflammation, glomerular, tubular renal function in chronic heart failure accompanied by chronic kidney disease

Abstract

The aim of the present study was to examine the severity and origin of the disorders of glomerular (creatinine (Cr), creatinine clearance (CrC), cystatin C), tubular (urine-β2-microglobulin) kidney function, changes of electrolyte balance (Na+, К+ in serum) and their connection with the activity and the formation of immune inflammation (TNF-α) and interstitial fibrosis (TGF-β1) in patients with chronic heart failure (CHF) and CHF accompanied by chronic kidney disease (CKD).