Endothelial function in patients with arterial hypertension and type 2 diabetes mellitus

Abstract

It has been known that impaired continuous basal release of Nitric oxide (NO) contributes to arterial hypertension and end-organ damage due the involvement in the regulation of vascular peripheral resistance and cardiovascular remodeling. But the degree of NO deficiency is diverse in hypertensive patients with obesity and this difference may be connected with age and gender.