Prognostic value of polymorphism of G-308A gene of the tumor necrosis factor-αin the progression of chronic heart failure in patients with ischemic heart disease and obesity
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Кравчун, Павло Григорович
Кадикова, Ольга Ігорівна
Риндіна, Наталія Геннадіївна
Крапівко, Світлана Олександрівна
Kravchun, Pavlo G.
Kadykova, Olga
Ryndina, Natalia
Krapivko, Svitlana
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The goal - to evaluate the role of polymorphism of G-308A gene tumor necrosis factor - α as a possible factor in the progression of chronic heart failure in patients with coronary heart disease and obesity. Conclusions. The presence of allele A and A / A genotype polymorphic locus G-308A TNF-α gene in patients with coronary artery disease with concomitant obesity was associated with progression of CHF, the formation of LV systolic dysfunction.
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Prognostic value of polymorphism of G-308A gene of the tumor necrosis factor-αin the progression of chronic heart failure in patients with ischemic heart disease and obesity / P. Kravchun, O. Kadykova, N. Ryndina, S. Krapivko // Archive of Clinical Medicine. – 2016. – Vol. 22, No. 1. – Р. 88–92.