State of the Blood-Air Barrier in Pediatric Acute Leukemia patients: prognosis for pulmonary complications
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Date
2023
Authors
Makieieva, Natalia
Koval, Victoria
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Abstract
The blood-air barrier (BAB) is a structural and functional part of the lungs, which is composed of epithelial, interstitial, and endothelial components. Studied markers IL-6, TGF-β in exhaled breath condensate (EBC) and serum VEGF-A are increased both during protocol treatment and in long-term remission, which proves BAB damage in children with acute leukemia (AL). Levels of IL-6 and TGF-β in EBC and VEGF-A in serum can be predictive for lung complications in pediatric acute leukemia patients. Assessment of BAB damage markers can be
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Keywords
acute leukemia, children, pulmonary complications, pneumonia, blood-air barrier, cytokines, interleukin-6, transforming growth factor β, vascular endothelial growth factor, 2023а
Citation
Makieieva N. State of the Blood-Air Barrier in Pediatric Acute Leukemia patients: prognosis for pulmonary complications [Electronic source] : [Online Poster] / N. Makieieva, V. Koval. – Kaunas, Lithuania, 2023.